"The needs of Your people are great, and their knowledge is scant" (Neilah service of Yom Kippur).

The Rebbe Maharash interprets this statement as follows: Why are their needs great? Because their knowledge is scant (i.e., narrow and limited).

We can derive two points from this:

The first is that the individual is not giving proper value to his essence - his spiritual being. As a result, he is on a constant search for more and more physical pleasures and luxuries, not realizing that this causes him to risk losing what he has and not be granted his true (spiritual) needs. The Tzemach Tzedek once compared this to oversized garments: not only don't they serve their ordinary purpose but they get ensnared in the wearer's legs and impede his walking altogether.

When a person develops a broad mind through the study of G-dly wisdom, however, materialism and the limitations of the physical world don't affect him, for material substance is of no significance to him. His desire and search are for spiritual values, and physicality matters to him only insofar as it relates to learning Torah and fulfilling its mitzvos.

Likkutei Sichos, vol. 1, p. 176